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Pedro Luis Rodriguez Egea

Email: prodriguez@ibmcp.upv.es

Teléfono: '+34 963 877 860

Extensión: 77860

Puesto: Investigador en Plantilla / Profesor de Investigación CSIC

Grupo: Abscisic Acid Signaling

Localización: Lab. 2.04

ORCID: 0000-0002-5886-9425

Biografía

Educación: Doctorado en Bioquímica y Biología Molecular (1994), Centro de Biología Molecular Severo Ochoa, Universidad Autónoma de Madrid, España.

Trayectoria profesional:

● Investigador del CSIC desde 2006 en el Instituto de Biología Molecular y Celular de Plantas. Promovido a Científico Titular en 2009 y a Profesor de Investigación en 2016.

● Profesor Ayudante de Bioquímica y Biología Molecular, 2003-2006. Universitat Politècnica de València.

● Investigador postdoctoral Ramón y Cajal, 1998-2003. Laboratorio del Prof. Ramón Serrano, Universitat Politècnica de València.

● Becario postdoctoral EMBO, 1995-1997. Laboratorio del Prof. Erwin Grill, ETH Zúrich, Suiza / TU Múnich, Alemania.

Autor de más de 100 artículos, 4 patentes, participación en 33 proyectos (20 como IP), Editor Asociado en Molecular Plant. El Dr. Rodríguez es un referente en el estudio de la señalización por ABA, con especial énfasis en su potencial biotecnológico para mejorar la tolerancia de las plantas a la sequía y la salinidad. Ha desempeñado un papel clave en el descubrimiento y caracterización de la nueva familia de receptores de ABA PYR/PYL y su conexión con las PP2Cs y SnRK2s.

Publicaciones destacadas

Bono M, Mayordomo C, Coego A, Illescas-Miranda J, Rivera-Moreno M, Infantes L, López-Carracedo P, Sanchez-Olvera M, Martin-Vasquez C, Pizzio GA, Merino J, Forment J, Merilo E, Estevez JC, Albert A, Rodriguez PL. (2025)
Structural insights into ABA receptor agonists reveal critical features to optimize and design a broad-spectrum ABA signaling activator.
Mol Plant. 2025 Sep 1;18(9):1526-1548. doi: 10.1016/j.molp.2025.07.014.
Merino J, Rivera-Moreno M, Bono M, Núñez-Villanueva D, González-Vega A, Mayordomo C, Infantes L, Chikhale R, Rodríguez PL, Albert A.
Natural modulators of abscisic acid Signaling: Insights into polyphenol-based antagonists and their role in ABA receptor regulation.
Plant Physiol Biochem. 2025 Oct;227:110155. doi: 10.1016/j.plaphy.2025.110155.
Bono M, Rivera-Moreno M, Albert A, Rodriguez PL. (2025)
Phosphorylation/dephosphorylation-mediated regulation of ABI1/2 activity and stability for fine-tuning ABA signaling.
Mol Plant. 2025 Jul 7;18(7):1103-1105. doi: 10.1016/j.molp.2025.05.006.
Xu X, Liu H, Praat M, Pizzio GA, Jiang Z, Driever SM, Wang R, Van De Cotte B, Villers SLY, Gevaert K, Leonhardt N, Nelissen H, Kinoshita T, Vanneste S, Rodriguez PL, van Zanten M, Vu LD, De Smet I. (2025)Stomatal opening under high temperatures is controlled by the OST1-regulated TOT3-AHA1 module. Nat Plants. 2025 Jan;11(1):105-117. doi: 10.1038/s41477-024-01859-w.
Bono M, Ferrer-Gallego R, Pou A, Rivera-Moreno M, Benavente JL, Mayordomo C, Deis L, Carbonell-Bejerano P, Pizzio GA, Navarro-Payá D, Matus JT, Martinez-Zapater JM, Albert A, Intrigliolo DS, Rodriguez PL. (2024)Chemical activation of ABA signaling in grapevine through the iSB09 and AMF4 ABA receptor agonists enhances water use efficiency.Physiol Plant. 2024 Nov-Dec;176(6):e14635. doi: 10.1111/ppl.14635.
Pizzio GA, Mayordomo C, Illescas-Miranda J, Coego A, Bono M, Sanchez-Olvera M, Martin-Vasquez C, Samantara K, Merilo E, Forment J, Estevez JC, Nebauer SG, Rodriguez PL. (2024)Basal ABA signaling balances transpiration and photosynthesis.Physiol Plant. 2024 Sep-Oct;176(5):e14494. doi: 10.1111/ppl.14494.
Eckardt,N.A., Avin-Wittenberg,T., Bassham,D.C., Chen,P., Chen,Q., Fang,J., Genschik,P., Ghifari,A.S., Guercio,A.M., Gibbs,D.J., Heese,M., Jarvis,R.P., Michaeli,S., Murcha,M.W., Mursalimov,S., Noir,S., Palayam,M., Peixoto,B., Rodriguez,P.L., Schaller,A., Schnittger,A., Serino,G., Shabek,N., Stintzi,A., Theodoulou,F.L., ÃœstÃ¼n,S., van Wijk,K.J., Wei,N., Xie,Q., Yu,F. and Zhang,H. (2024). The lowdown on breakdown: Open questions in plant proteolysis.Plant Cell 2024 Jul 9:koae193. doi: 10.1093/plcell/koae193
Sanchez-Olvera, M., Martin-Vasquez, C., Mayordomo, C., Illescas-Miranda, J., Bono, M., Coego, A., Alonso, J., Hernández-González, M., Jiménez-Arias, D., Forment, J., Albert, A., Granell, A., Borges, A. A., Rodriguez, P. L* (2024). ABA-receptor agonist iSB09 decreases soil water consumption and increases tomato CO2 assimilation and water use efficiency under drought stress. Environmental and Experimental Botany 225, 105847.https://doi.org/10.1016/j.envexpbot.2024.105847
Morales-Sierra,S., Luis,J.C., Jimenez-Arias,D., Rancel-Rodriguez,N.M., Coego,A., Rodriguez,P.L., Cueto,M. and Borges,A.A. (2023). Biostimulant activity of Galaxaura rugosa seaweed extracts against water deficit stress in tomato seedlings involves activation of ABA signaling.Front Plant Sci. 14, 1251442. doi: 10.3389/fpls.2023.1251442
Jiménez-Arias D, Morales-Sierra S, Suárez E, Lozano-Juste J, Coego A, Estevez JC, Borges AA, Rodriguez PL* (2023). Abscisic acid mimic-fluorine derivative 4 (AMF4) alleviates water deficit stress by regulating ABA-responsive genes, proline accumulation, CO2 assimilation, water use efficiency and better nutrient uptake in tomato plants. Front Plant Sci. 14:1191967. doi: 10.3389/fpls.2023.1191967
Yang C, Li X, Chen S, Liu C, Yang L, Li K, Liao J, Zheng X, Li H, Li Y, Zeng S, Zhuang X, Rodriguez PL, Luo M, Wang Y, Gao C. (2023).ABI5-FLZ13 Module Transcriptionally Represses Growth-related Genes to Delay Seed Germination in Response to ABA. Plant Commun. 2023 Jun 9:100636. doi: 10.1016/j.xplc.2023.100636.
Lozano-Juste J, Infantes L, Garcia-Maquilon I, Ruiz-Partida R, Merilo E, Benavente JL, Velazquez-Campoy A, Coego A, Bono M, Forment J, Pampín B, Destito P, Monteiro A, Rodríguez R, Cruces J, Rodriguez PL*, Albert A* (2023). Structure-guided engineering of a receptor-agonist pair for inducible activation of the ABA adaptive response to drought.Sci Adv. 2023 Mar 10;9(10):eade9948. doi: 10.1126/sciadv.ade9948.
Hirt H, Al-Babili S, Almeida-Trapp M, Martin A, Aranda M, Bartels D, Bennett M, Blilou I, Boer D, Boulouis A, Bowler C, Brunel-Muguet S, Chardon F, Colcombet J, Colot V, Daszkowska-Golec A, Dinneny JR, Field B, Froehlich K, Gardener CH, Gojon A, Gomès E, Gomez-Alvarez EM, Gutierrez C, Havaux M, Hayes S, Heard E, Hodges M, Alghamdi AK, Laplaze L, Lauersen KJ, Leonhardt N, Johnson X, Jones J, Kollist H, Kopriva S, Krapp A, Masson ML, McCabe MF, Merendino L, Molina A, Moreno Ramirez JL, Mueller-Roeber B, Nicolas M, Nir I, Orduna IO, Pardo JM, Reichheld JP, Rodriguez PL, Rouached H, Saad MM, Schlögelhofer P, Singh KA, De Smet I, Stanschewski C, Stra A, Tester M, Walsh C, Weber APM, Weigel D, Wigge P, Wrzaczek M, Wulff BBH, Young IM (2023). PlantACT! - how to tackle the climate crisis. Trends Plant Sci. 2023 28(5):537-543. doi: 10.1016/j.tplants.2023.01.005.
Chen W, Zhou H, Xu F, Yu M, Coego A, Rodriguez L, Lu Y, Xie Q, Fu Q, Chen J, Xu G, Wu D, Li X, Li X, Jaillais Y, Rodriguez PL, Zhu S, Yu F. (2023). CAR modulates plasma membrane nano-organization and immune signaling downstream of RALF1-FERONIA signaling pathway. New Phytol. 2023 Mar;237(6):2148-2162. doi: 10.1111/nph.18687
Pizzio GA, Rodriguez PL* (2022). Dual regulation of SnRK2 signaling by Raf-like MAPKKKs. Mol Plant. 2022 Aug 1;15(8):1260-1262. doi: 10.1016/j.molp.2022.07.002.
Infantes L, Rivera-Moreno M, Daniel-Mozo M, Benavente JL, Ocaña-Cuesta J, Coego A, Lozano-Juste J, Rodriguez PL, Albert A (2022). Structure-Based Modulation of the Ligand Sensitivity of a Tomato Dimeric Abscisic Acid Receptor Through a Glu to Asp Mutation in the Latch Loop. Front Plant Sci. 2022 Jun 6;13:884029. doi: 10.3389/fpls.2022.884029. eCollection 2022.
Franco-Aragón D, García-Maquilón I, Manicardi A, Rodríguez PL, Lozano-Juste J (2022). Evaluation of the Anti-transpirant Activity of ABA Receptor Agonists in Monocot and Eudicot Plants. Methods Mol Biol. 2022;2494:229-238. doi: 10.1007/978-1-0716-2297-1_16.
Garcia-Maquilon I, Lozano-Juste J, Alrefaei AF, Rodriguez PL* (2022). Hydrotropism: Analysis of the Root Response to a Moisture Gradient. Methods Mol Biol. 2022;2494:17-24. doi: 10.1007/978-1-0716-2297-1_2.
Pizzio GA, Mayordomo C, Lozano-Juste J, Garcia-Carpintero V, Vazquez-Vilar M, Nebauer SG, Kaminski KP, Ivanov NV, Estevez JC, Rivera-Moreno M, Albert A, Orzaez D, Rodriguez PL* (2022). PYL1- and PYL8-like ABA Receptors of Nicotiana benthamiana Play a Key Role in ABA Response in Seed and Vegetative Tissue. Cells. 2022 Feb 24;11(5):795. doi: 10.3390/cells11050795.
Belda-Palazón B, Rodriguez PL (2022). Microscopic Imaging of Endosomal Trafficking of ABA Receptors. Methods Mol Biol. 2022;2462:59-69. doi: 10.1007/978-1-0716-2156-1_5
Julian J, Coego A, Alrefaei AF, Rodriguez PL* (2022). Affinity Purification of Ubiquitinated Proteins Using p62-Agarose to Assess Ubiquitination of Clade A PP2Cs. Methods Mol Biol. 2022;2462:45-57. doi: 10.1007/978-1-0716-2156-1_4.
Miao R, Russinova E, Rodriguez PL* (2022). Tripartite hormonal regulation of plasma membrane H+-ATPase activity. Trends Plant Sci Jun;27(6):588-600 https://doi.org/10.1016/j.tplants.2021.12.011
Alberto Coego, Jose Julian, Jorge Lozano-Juste, Gaston A. Pizzio, Abdulwahed F. Alrefaei and Pedro L. Rodriguez (2021). Ubiquitylation of ABA receptors and protein phosphatase 2C coreceptors to modulate ABA signaling and stress response. Int. J. Mol. Sci 22, 7103.
Rui Miao, Wei Yuan, Yue Wang, Irene García-Maquilón, Xiaolin Dang, Suchang Huang, Ying Li, Jianhua Zhang, Yiyong Zhu, Pedro L. Rodriguez, Weifeng Xu (2021). Low ABA concentration promotes root growth and hydrotropism through relief of ABA INSENSITIVE 1-mediated inhibition of plasma membrane H+-ATPase 2. Science Advances 7 (12): eabd4113
Irene García-Maquilón, Pedro L. Rodriguez, Aditya S. Vaidya, Jorge Lozano-Juste (2021). A luciferase reporter assay to identify chemical activators of ABA signaling. Plant Chemical Genomics Methods Mol Biol. 2021;2213:113-121. doi: 10.1007/978-1-0716-0954-5_10
Jorge Lozano-Juste, Irene García-Maquilón, José Brea, Rocío Piña, Armando Albert, Pedro L. Rodriguez, María Isabel Loza. Plant Chemical Genomics (2021). Identification of ABA receptor agonists using a multiplexed high-throughput chemical screening. Methods Mol Biol. 2021;2213:99-111. doi: 10.1007/978-1-0716-0954-5_9.
Garcia-Maquilon,I., Coego,A., Lozano-Juste,J., Messerer,M., de Ollas,C., Julian,J., Ruiz-Partida,R., Pizzio,G., Belda-Palazon,B., Gomez-Cadenas,A., Mayer,K.F.X., Geiger,D., Alquraishi,S.A., Alrefaei,A.F., Ache,P., Hedrich,R. and Rodriguez,P.L. (2021). PYL8 ABA receptors of Phoenix dactylifera play a crucial role in response to abiotic stress and are stabilized by ABA. J.Exp.Bot. 72(2):757-774
Belda-Palazon,B., Adamo,M., Valerio,C., Ferreira,L.J., Confraria,A., Reis-Barata,D., Rodrigues,A., Meyer,C., Rodriguez,P.L. and Baena-Gonzalez,E. (2020). A dual function of SnRK2 kinases in the regulation of SnRK1 and plant growth. Nature Plants 6(11):1345-1353
Lozano-Juste,J., Alrefaei,A.F. and Rodriguez,P.L. (2020). Plant Osmotic Stress Signaling: MAPKKKs Meet SnRK2s. Trends Plant Sci. Dec;25(12):1179-1182
Garcia-Andrade,J., Gonzalez,B., Gonzalez-Guzman,M., Rodriguez,P.L. and Vera,P. (2020). The Role of ABA in Plant Immunity is Mediated through the PYR1 Receptor. Int. J. Mol. Sci. 21, E5852
Lozano-Juste,J., Garcia-Maquilon,I., Ruiz-Partida,R. and Rodriguez,P.L. (2020). Drug Discovery for Thirsty Crops. Trends Plant Sci. Sep;25(9):844-846
Belda-Palazon, B., and Rodriguez, P. L. (2020). Degradation of abscisic acid receptors through the endosomal pathway. Methods Mol Biol. 2177:35-48. Book "Plant Endosomes": Methods and Protocols
Fernandez, M. A., Belda-Palazon, B., Julian, J., Coego, A., Lozano-Juste, J., Inigo, S., Rodriguez, L., Bueso, E., Goossens, A., and Rodriguez, P. L. (2020). RBR-type E3 ligases and the Ub-conjugating enzyme UBC26 regulate ABA receptor levels and signaling. Plant Physiol. 182(4):1723-1742
Dittrich, M., Mueller, H. M., Bauer, H., Peirats-Llobet, M., Rodriguez, P. L., Geilfus, C. M., Carpentier, S. C., Al Rasheid, K. A. S., Kollist, H., Merilo, E., Herrmann, J., Muller, T., Ache, P., Hetherington, A. M., and Hedrich, R. (2019). The role of Arabidopsis ABA receptors from the PYR/PYL/RCAR family in stomatal acclimation and closure signal integration. Nature Plants 5(9), 1002-1011.
Garcia-Leon, M., Cuyas, L., El-Moneim, D., Rodriguez, L., Belda-Palazon, B., Fernandez, Y., Roux, B., Zamarreño, A.M., Garcia-Mina, J.M., Nussaume, L., Rodriguez, P.L., Paz-Ares, J., Leonhardt, N., and Rubio, V. (2019). Arabidopsis ALIX Regulates Stomatal Aperture and Turnover of Abscisic Acid Receptors. Plant Cell 31(10):2411-2429.
Julian, J., Coego, A., Lozano-Juste, J., Lechner, E., Wu, Q., Zhang, X., Merilo, E., Belda-Palazon, B., Park, S. Y., Cutler, S. R., An, C., Genschik, P., and Rodriguez, P. L. (2019). The MATH-BTB BPM3 and BPM5 subunits of Cullin3-RING E3 ubiquitin ligases target PP2CA and other clade A PP2Cs for degradation. Proc.Natl.Acad.Sci.USA. 116(31):15725-15734
Lozano-Juste, J., Masi, M., Cimmino, A., Clement, S., Fernandez, M. A., Antoni, R., Meyer, S., Rodriguez, P. L., and Evidente, A. (2019). The fungal sesquiterpenoid pyrenophoric acid B uses the plant ABA biosynthetic pathway to inhibit seed germination. J.Exp.Bot. 70(19):5487-5494.
Li, H., Li, Y., Zhao, Q., Li, T., Wei, J., Li, B., Shen, W., Yang, C., Zeng, Y., Rodriguez, P. L., Zhao, Y., Jiang, L., Wang, X., and Gao, C. (2019). The plant ESCRT component FREE1 shuttles to the nucleus to attenuate abscisic acid signalling. Nature Plants. 5(5):512-524.
Pedro L. Rodriguez, Jorge Lozano-Juste and Armando Albert. PYR/PYL/RCAR ABA receptors (2019). Advances in Botanical Research, Abscisic Acid in Plants, volume 92, pages 51-82. Edited by M. Seo and A. Marion-Poll. Elsevier. doi:10.1016/bs.abr.2019.05.003
Belda-Palazon, B., Julian, J., Coego, A., Wu, Q., Zhang, X., Batistic, O., Alquraishi, S. A., Kudla, J., An, C., and Rodriguez, P. L. (2019). ABA inhibits myristoylation and induces shuttling of the RGLG1 E3 ligase to promote nuclear degradation of PP2CA. Plant J. doi10.1111/tpj.14274
Belda-Palazon, B., Gonzalez-Garcia, M. P., Lozano-Juste, J., Coego, A., Antoni, R., Julian, J., Peirats-Llobet, M., Rodriguez, L., Berbel, A., Dietrich, D., Fernandez, M. A., Madueno, F., Bennett, M. J., and Rodriguez, P. L. (2018). PYL8 mediates ABA perception in the root through non-cell-autonomous and ligand-stabilization-based mechanisms. Proc.Natl.Acad.Sci. U.S.A 115, E11857-E11863
Moreno-Alvero,M., Yunta,C., Gonzalez-Guzman,M., Lozano-Juste,J., Benavente,J.L., Arbona,V., Menendez,M., Martinez-Ripoll,M., Infantes,L., Gomez-Cadenas,A., Rodriguez,P.L.* and Albert,A.* (2017). Structure of Ligand-Bound Intermediates of Crop ABA Receptors Highlights PP2C as Necessary ABA Co-receptor. Molecular Plant 10, 1250-1253
Rodriguez PL (2016). ABA catabolism generates PA, a molecule able to activate a subset of ABA receptors. Molecular Plant 9, 1448-1450
Wu,Q., Zhang,X., Peirats-Llobet,M., Belda-Palazon,B., Wang,X., Cui,S., Yu,X., Rodriguez,P.L.* and An,C. *(2016). Ubiquitin Ligases RGLG1 and RGLG5 Regulate Abscisic Acid Signaling by Controlling the Turnover of Phosphatase PP2CA. Plant Cell 28:2178-2196
Belda-Palazon,B., Rodriguez,L., Fernandez,M.A., Castillo,M.C., Anderson,E.A., Gao,C., Gonzalez-Guzman,M., Peirats-Llobet,M., Zhao,Q., De Winne,N., Gevaert,K., De Jaeger,G., Jiang,L., Leon,J., Mullen,R.T. and Rodriguez,P.L. (2016). FYVE1/FREE1 Interacts with the PYL4 ABA Receptor and Mediates its Delivery to the Vacuolar Degradation Pathway. Plant Cell 28:2291-2311
Antoni,R., Dietrich,D., Bennett,M.J. and Rodriguez,P.L. (2016). Hydrotropism: Analysis of the Root Response to a Moisture Gradient. Methods Mol. Biol. 1398, 3-9.
Diaz,M., Sanchez-Barrena,M.J., Gonzalez-Rubio,J.M., Rodriguez,L., Fernandez,D., Antoni,R., Yunta,C., Belda-Palazon,B., Gonzalez-Guzman,M., Peirats-Llobet,M., Menendez,M., Boskovic,J., Marquez,J.A., Rodriguez,P.L. and Albert,A. (2016). Calcium-dependent oligomerization of CAR proteins at cell membrane modulates ABA signaling. Proc.Natl.Acad.Sci.U.S.A Jan 19;113(3):E396-405
Peirats-Llobet,M., Han,S.K., Gonzalez-Guzman,M., Jeong,C.W., Rodriguez,L., Belda-Palazon,B., Wagner,D. and Rodriguez,P.L. (2016). A direct link between abscisic acid sensing and the chromatin remodeling ATPase BRAHMA via core ABA signaling pathway components. Mol Plant. 9(1):136-47.
Rodriguez, P.L. and Lozano-Juste, J. (2015). Unnatural agrochemical ligands for engineered abscisic acid receptors. Trends in Plant Science 20(6):330-2.
Gonzalez-Guzman,M., Rodriguez,L., Lorenzo-Orts,L., Pons,C., Sarrion-Perdigones,A., Fernandez,M.A., Peirats-Llobet,M., Forment,J., Moreno-Alvero,M., Cutler,S.R., Albert,A., Granell,A. and Rodriguez,P.L. (2014). Tomato PYR/PYL/RCAR abscisic acid receptors show high expression in root, differential sensitivity to the abscisic acid agonist quinabactin, and the capability to enhance plant drought resistance. J Exp Bot 65, 4451-4464.
Bueso E, Rodriguez L, Lorenzo-Orts L, Gonzalez-Guzman M, Sayas E, Muñoz-Bertomeu J, Ibañez C, Serrano R, Rodriguez P.L. (2014) The single subunit RING-type E3 ubiquitin ligase RSL1 targets PYL4 and PYR1 ABA receptors in plasma membrane to modulate abscisic acid signaling. Plant J. 80, 1057-1071.
Rodriguez, L., Gonzalez-Guzman, M., Diaz, M., Rodrigues, A., Peirats-Llobet, M., Izquierdo-Garcia, A.C., Antoni, R., Marquez, J.A. Mulet, J.M. Albert, A. and Rodriguez P.L. (2014). C2-domain abscisic acid-related proteins mediate the interaction of PYR/PYL/RCAR abscisic acid receptors with the plasma membrane. Plant Cell 26, 26(12):4802-20
Pizzio, G.A., Rodriguez, L., Antoni, R., Gonzalez-Guzman, M., Yunta, C., Merilo, E., Kollist, H., Albert, A., Rodriguez P.L. (2013) The PYL4 A194T mutant uncovers a key role of PYL4-PP2CA interaction for ABA signaling and plant drought resistance. Plant Physiology 163: 441-455.
Antoni, R., Gonzalez-Guzman, M., Rodriguez, L., Peirats-Llobet, M., Pizzio, G.A., Fernandez, M.A., De Winne N., De Jaeger G., Dietrich, D., Bennett M.J., Rodriguez P.L (2013). PYRABACTIN RESISTANCE1-LIKE8 plays an important role for the regulation of abscisic acid signaling in root. Plant Physiology 161: 931-941.
Gonzalez-Guzman, M., Pizzio, G.A, Antoni, R., Vera-Sirera, F., Merilo, E., Bassel, G.W., Fernandez, M.A., Holdsworth, M., Perez-Amador, M.A., Kollist, H. and Rodriguez, P.L (2012). Abscisic acid perception via PYR/PYL/RCAR receptors plays a major role to regulate stomatal aperture and ABA transcriptional response. Plant Cell 24: 2483-2496.
Antoni, R., Gonzalez-Guzman, M., Rodriguez, L., Rodrigues, A., Pizzio, G.A. and Rodriguez, P.L (2012). Selective inhibition of clade A phosphatases type 2C by PYR/RCAR/RCAR abscisic acid receptors Plant Physiology 158, 970-980.
Dupeux, F., Antoni, R., Betz, K., Santiago, J., Gonzalez-Guzman, M., Rodriguez, L., Rubio, S., Park, S-Y., Cutler, S.R., Rodriguez, P.L* and Marquez, J.A. (2011). Modulation of ABA signaling in vivo by an engineered receptor-insensitive PP2C allele. Plant Physiology 156, 106-116.
Cutler, S.R., Rodriguez, P.L., Finkelstein, R.R., Abrams, S.R. (2010). Abscisic acid: emergence of a core signaling network. Annu. Rev. Plant Biol. 61, 651-679.
Santiago, J., Rodrigues, A., Saez, A., Rubio, S., Antoni, R., Park, S-Y., Dupeux, F., Marquez, J.A., Cutler, S.R. and Rodriguez, P.L. (2009). Modulation of drought resistance by the abscisic acid-receptor PYL5 through inhibition of clade A PP2Cs. Plant J 60, 575-588.
Rubio, S., Rodrigues, A., Saez, A., Dizon, M.B., Galle, A., Kim, T., Santiago, J., Flexas, J., Schroeder, J.I.S. and Rodriguez, P.L. (2009). Triple loss-of-function of protein phosphatases type 2C leads to partial constitutive response to endogenous ABA. Plant Physiology 150, 1345-1355.
Santiago, J., Dupeux, F., Round, A., Antoni, R., Park, S-Y., Jamin, M., Cutler, S.R., Rodriguez, P.L. and Marquez, J.A. (2009). The abscisic acid receptor PYR1 in complex with abscisic acid. Nature 462, 660-664
Fujii, H., Chinnusamy, V., Rodrigues, A., Rubio, S., Antoni, R., Park, S-Y., Cutler, S.R., Sheen, J., Rodriguez, P.L. and Zhu, J-K. (2009). In vitro reconstitution of an ABA signalling pathway. Nature 462, 665-668.
Park, S-Y., Fung, P., Nishimura, N., Jensen, D.R., Fujii, H., Zhao, Y., Lumba, S., Santiago, J., Rodrigues, A., Chow, T-S., Alfred, S.E., Bonetta, D., Finkelstein, R., Provart, N.J., Desveaux, D., Rodriguez, P.L., McCourt, P., Zhu, J-K, Schroeder, J.I., Volkman, B.F. and Cutler, S.R. (2009). Abscisic acid inhibits type 2C protein phosphatases via the PYR/PYL family of ABA-binding START proteins. Science 324, 1068-1071.
Saez, A., Rodrigues, A, Santiago, J., Rubio, S. and Rodríguez, P.L. (2008). HAB1-SWI3B interaction reveals a link between abscisic acid signaling and putative SWI/SNF chromatin remodeling complexes. Plant Cell 20, 2972-2988.
Saez, A., Robert, N., Maktabi, M., Schroeder, J.I, Serrano, R. and Rodriguez, P.L. (2006). Enhancement of abscisic acid sensitivity and reduction of water consumption in Arabidopsis by combined inactivation of the protein phosphatases type 2C ABI1 and HAB1. Plant Physiol 141, 1389-1399.
Saez, A., Apostolova, N., Gonzalez-Guzman, M., Gonzalez-Garcia, M.P., Nicolas, C., Lorenzo, O. and Rodriguez, P.L. (2004). Gain-of-function and loss-of-function phenotypes of the protein phosphatase 2C HAB1 reveal its role as a negative regulator of abscisic acid signalling. Plant J 37, 354-369.
Gonzalez-Guzman, M., Apostolova, N., Belles, J.M., Barrero, J.M., Piqueras, P., Ponce, M.R., Micol, J.L., Serrano, R. and Rodriguez, P.L. (2002). The short-chain alcohol dehydrogenase ABA2 catalyzes the conversion of xanthoxin to abscisic aldehyde. Plant Cell 14, 1833-1846.