GENERAL DESCRIPTION OF SCIENTIFIC INTERESTS:

Ion homeostasis is a dynamic process and a fundamental requirement for all organisms. Many different minerals are essential for key biochemical processes, but excessive accumulation of these elements can be toxic. Therefore, all living organisms have evolved efficient systems for acquiring and storing these elements, as well as robust mechanisms to maintain homeostatic concentrations that prevent toxicity and allow them to respond to environmental changes.

Potassium is a key monovalent cation required for multiple aspects of cellular growth and survival, such as balancing negative charges of macromolecules, maintaining electroneutrality, cell turgor and volume, enzyme activity, protein synthesis, and maintaining membrane potential and intracellular pH. The long-term general goal of our research group is to generate new knowledge on the regulation of potassium transporters in both plants and yeast, with future applications in biotechnological approaches to improve drought tolerance in crops.

CURRENT PROJECTS:

We are currently conducting two major lines of research. One focuses on basic science and the generation of new knowledge, and the other is more applied and carried out in collaboration with an industrial partner. Both are related to the study of molecular mechanisms involved in plant responses to stress, particularly abiotic stress. Our scientific interests can be summarized as follows:

Basic science:

In plants, beyond the general physiological roles described above for potassium at the cellular level, this cation also plays a key role at the whole-plant level, participating in crucial processes such as stomatal opening, which regulates water loss through transpiration and plant desiccation. Inward-rectifying channels are responsible for potassium uptake in guard cells and are essential for stomatal opening. KAT1 and its close homolog KAT2 are the main inward-rectifying channels expressed in guard cells. Our current project focuses on the characterization of 14 proteins identified through a Split-Ubiquitin protein–protein interaction screen, as potential interactors of the KAT1 potassium channel in the model plant Arabidopsis thaliana.

We are using various biochemical and genetic approaches to validate these interactions and analyze their effect on KAT1 activity in plants. The identification of physiologically relevant regulators of K⁺ channels will contribute to the design of strategies that may impact both drought tolerance and susceptibility to pathogens, given that these pores are responsible for CO₂ uptake and water loss through transpiration, as well as serving as entry points for certain pathogens.

Applied science with industrial partners:

Our second major research focus, initiated in 2018 in collaboration with the company SAKATA, centers on the analysis of proteomic and metabolomic profiles in different broccoli cultivars with varying levels of tolerance to abiotic stresses (drought and salinity). The objective is to identify proteins and/or metabolites with differential accumulation that could be used to predict the behavior of uncharacterized cultivars under adverse field conditions. As a complementary approach, we leverage our expertise with the yeast model system Saccharomyces cerevisiae to overexpress genes from a tolerant broccoli cultivar, aiming to identify those capable of conferring tolerance to salinity and drought. With these approaches, we hope to provide SAKATA with a useful toolbox for both cultivar selection and breeding programs.

We have also developed a fast and cost-effective system to evaluate natural extracts with potential use as biostimulants, based on the use of the model systems Arabidopsis thaliana and Saccharomyces cerevisiae. We have used this system to evaluate products provided by various companies and to design new formulations. Currently, in collaboration with the company CALDIC, we are uncovering the molecular basis of the abiotic stress tolerance conferred by new biostimulant formulations and conducting field trials to assess their efficacy in different crops.

Mulet, J.M.; Benito, P.; Celdrán, M.; Yenush, L.; Porcel, R. (2025). Impact of Different Microbial Biostimulants and Salt Stress on the Endophytome of the Edible Part of Lettuce and Tomato Plants. Foods, 14, 3366. https://doi.org/10.3390/foods14193366

Benito, P., Trigueros, S., Celdrán, M. Sánchez, V., Coronado, A., Bellón, J., Arbona, V., González-Guzmán, M., Porcel, R., Yenush, L., Mulet, J.M. (2025). The combined effect of a newly designed biostimulant and a plant growth-promoting bacterium increases tomato yield under salt stress by increasing the cytokinin isopentenyladenine riboside content. Chem. Biol. Technol. Agric. 12, 117. https://doi.org/10.1186/s40538-025-00825-8

Locascio, A., Montoliu-Silvestre, E., Nieves-Cordones, M., Petsch, S., Fuchs, A., Bou, C., Navarro-Martínez, A., Porcel, R., Andrés-Colás, N., Rubio, F., Mulet, JM., Yenush, L. (2025). ROOT PHOTOTROPISM 2 (RPT2) is a KAT1 potassium channel regulator required for its accumulation. Plant Physiology and Biochemistry, Volume 224, 109922, ISSN 0981-9428, https://doi.org/10.1016/j.plaphy.2025.109922.

Montesinos, C., Benito, P., Porcel, R., Bellón, J., González-Guzmán, M., Arbona, V., Yenush, L., Mulet, J.M. Field evaluation and characterization of a novel biostimulant for broccoli (Brassica oleracea var. italica) cultivation under drought and salt stress which increases antioxidant, glucosinolate and phytohormone content. (2024). Scientia Horticulturae, Volume 338, 113584, ISSN 0304-4238, https://doi.org/10.1016/j.scienta.2024.113584.

Benito, P., Celdrán, M., Bellón, J., Arbona, V., González‐ Guzmán, M., Porcel, R., Yenush, L., and Mulet, J.M. (2024). The combination of a microbial and a non‐microbial biostimulant increases yield in lettuce (Lactuca sativa) under salt stress conditions by up‐regulating cytokinin biosynthesis. J. Integr. Plant Biol. 00: 1–18.

Porcel, R. (2024). The Adaptation of Crops to the Environment under Climate Change: Physiological and Agronomic Strategies—Volume II. Agronomy, 14, 1635. https:// doi.org/10.3390/agronomy14081635

González-García A, Kanli M, Wisowski N, Montoliu-Silvestre E, Locascio A, Sifres A, Gómez M, Ramos J, Porcel R, Andrés-Colás N, Mulet JM, Yenush L. (2024). Maternal Embryo Effect Arrest 31 (MEE31) is a moonlighting protein involved in GDP-D-mannose biosynthesis and KAT1 potassium channel regulation. Plant Sci. Jan;338:111897. doi: 10.1016/j.plantsci.2023.111897.

Mulet JM, Campos F, Yenush L (2023) Ion homeostasis in plant stress and development, volume II. Front Plant Sci. Aug 11;14:1264817. doi: 10.3389/fpls.2023.1264817.

Mulet JM, Porcel R, Yenush L (2023) Modulation of potassium transport to increase abiotic stress tolerance in plants. J. Exp. Bot., Vol. 74, No. 19 pp. 5989–6005

Porcel (2023) The Adaptation of Crops to the Environment under Climate Change: Physiological and Agronomic Strategies Agronomy, 13, 938.

Benito P., Bellón J, Porcel R, Yenush L, Mulet JM.  (2023) The Biostimulant, Potassium Humate Ameliorates Abiotic Stress in Arabidopsis thaliana by Increasing Starch Availability International. Journal of Molecular Sciences, 24(15), 12140

Chevilly S, Dolz-Edo L, Blanca J, Yenush L, Mulet JM (2023) Identification of Distinctive Primary Metabolites Influencing Broccoli (Brassica oleracea, var. Italica) Taste Foods, 12(2), 339

Benito P., Ligorio D, Bellón J, Yenush L, Mulet JM.  (2023) Use of Yucca (Yucca schidigera) Extracts as Biostimulants to Promote Germination and Early Vigor and as Natural Fungicides. Plants, 12(2), 274

Benito P., Ligorio D, Bellón J, Yenush L, Mulet JM.  (2022) A fast method to evaluate in a combinatorial manner the synergistic effect of different biostimulants for promoting growth or tolerance against abiotic stress Plant Methods, 2022, 18(1), 111

Chevilly S, Dolz-Edo L, Martínez-Sánchez G, Morcillo L, Vilagrosa A, López-Nicolás JM, Blanca J, Yenush L, Mulet JM. (2021) Distinctive Traits for Drought and Salt Stress Tolerance in Melon (Cucumis melo L.) Front Plant Sci. 2021 Nov 4;12:777060

Bissoli G, Bono M, Martínez-Almonacid I, Moreno-Peris E, Renard J, Espinosa A, Naranjo MÁ, Yenush L, Fita A, Serrano R, Rodríguez-Burruezo A, Bueso E. (2021) Seed coat lignification level is crucial in Capsicum spp seed longevity Physiol Plant. 2021 Nov 19:e13600

Chevilly S, Dolz-Edo L, Morcillo L, Vilagrosa A, López-Nicolás JM, Yenush L, Mulet JM. (2021) Identification of distinctive physiological and molecular responses to salt stress among tolerant and sensitive cultivars of broccoli (Brassica oleracea var. Italica) BMC Plant Biol. 2021 Oct 25;21(1):488

Chevilly S, Dolz-Edo L, López-Nicolás JM, Morcillo L, Vilagrosa A, Yenush L, Mulet JM. (2021) Physiological and Molecular Characterization of the Differential Response of Broccoli (Brassica oleracea var. Italica) Cultivars Reveals Limiting Factors for Broccoli Tolerance to Drought Stress. J Agric Food Chem. 2021 Sep 8;69(35):10394

Mulet JM, Campos F, Yenush L. (2020) Ion Homeostasis in Plant Stress and Development Front Plant Sci. 2020 Nov 20;11:618273

Vazquez-Vilar M, Gandía M, García-Carpintero V, Marqués E, Sarrion-Perdigones A, Yenush L, Polaina J, Manzanares P, Marcos JF, Orzaez D. (2020) Multigene Engineering by GoldenBraid Cloning: From Plants to Filamentous Fungi and Beyond Curr Protoc Mol Biol. 2020 Mar;130(1):e116

R Saporta, C Bou, V Frías, JM Mulet (2019). A Method for a Fast Evaluation of the Biostimulant Potential of Different Natural Extracts for Promoting Growth or Tolerance against Abiotic Stress Agronomy 9 (3), 143

A Locascio, MC Marques, G García-Martínez, C Corratgé-Faillie (2019) BCL2-ASSOCIATED ATHANOGENE4 Regulates the KAT1 Potassium Channel and Controls Stomatal Movement Plant Physiology 181 (3), 1277-1294

A Locascio, N Andrés-Colás, JM Mulet, L Yenush (2019) Saccharomyces cerevisiae as a tool to investigate plant potassium and sodium transporters Int. J. Mol. Sci. 20 (9), 2133

A Bustamante, MC Marques, A Sanz-Carbonell, JM Mulet, G Gomez (2018) Alternative processing of its precursor is related to miR319 decreasing in melon plants exposed to cold. Scientific Reports 8 (1), 15538

R Porcel, A Bustamante, R Ros, R Serrano, JM Mulet Salort (2018) BvCOLD1: A novel aquaporin from sugar beet (Beta vulgaris L.) involved in boron homeostasis and abiotic stress Plant, Cell & Environment 41 (12), 2844-2857

Hernanz-Koers M, Gandía M, Garrigues S, Manzanares P, Yenush L, Orzaez D, Marcos JF (2018) FungalBraid: A GoldenBraid-based modular cloning platform for the assembly and exchange of DNA elements tailored to fungal synthetic biology Fungal Genet Biol;116:51-61

Primo C, Ferri-Blázquez A, Loewith R, Yenush L (2017) Reciprocal Regulation of Target of Rapamycin Complex 1 and Potassium Accumulation. The Journal of Biological Chemistry 292: 563-574

Taibi K, del Campo AD, Aguado A, Mulet JM (2016) Early establishment response of different Pinus nigra ssp salzmanii seed sources on contrasting environments: Implications for future reforestation programs and assisted population migration Journal of Environmental Management 171: 184-194

Yenush L (2016) Potassium and Sodium Transport in Yeast Advances in Experimental Medicine and Biology 892: 187-228

Petrezselyova S, Lopez-Malo M, Canadell D, Roque A, Serra-Cardona A, Marquea MC, Vilaprinyo E, Alves R, Yenush L, Arino J (2016) Regulation of the Na+/K+-ATPase Ena1 Expression by Calcineurin/Crz1 under High pH Stress: A Quantitative Study Plos One 11: e0158424

Llopis-Torregrosa V, Ferri-Blazquez A, Adam-Artigues A, Deffontaines E, van Heusden GPH, Yenush L (2016) Regulation of the Yeast Hxt6 Hexose Transporter by the Rod1 alpha-Arrestin, the Snf1 Protein Kinase, and the Bmh2 14-3-3 Protein. The Journal of biological chemistry 291: 14973-14985

Marqués MC, Zamarbide-Forés S, Pedelini L, Llopis-Torregrosa V, Yenush L (2015) A functional Rim101 complex is required for proper accumulation of the Ena1 Na+-ATPase protein in response to salt stress in Saccharomyces cerevisiae FEMS Yeast Research 15: fov017

Mattiazzi Ušaj M, Prelec M, Brložnik M, Primo C, Curk T, Ščančar J, Yenush L, Petrovič U (2015) Yeast Saccharomyces cerevisiae adiponectin receptor homolog Izh2 is involved in the regulation of zinc, phospholipid and pH homeostasis Metallomics 7: 1338-1351

Bueso E, Muñoz-Bertomeu J, Campos F, Brunaud V, Martinez L, Sayas E, Ballester P, Yenush L, Serrano R (2014) ARABIDOPSIS THALIANA HOMEOBOX 25 uncovers a role for gibberellins in seed longevity Plant Physiology 164: 999-1010

Ariño J, Aydar E, Drulhe S, Ganser D, Jorrín J, Kahm M, Krause F, Petrezsélyová S, Yenush L, Zimmermannová O, van Heusden GP, Kschischo M, Ludwig J, Palmer C, Ramos J, Sychrová H (2014) Systems biology of monovalent cation homeostasis in yeast: the translucent contribution Advances in Microbial Physiology 64: 1-63

Mulet JM, Llopis-Torregrosa V, Primo C, Marqués MC, Yenush L (2013) Endocytic regulation of alkali metal transport proteins in mammals, yeast and plants Current Genetics 59: 207-230

Roque E, Serwatowska J, Cruz Rochina M, Wen J, Mysore KS, Yenush L, Beltrán JP, Cañas LA (2013) Functional specialization of duplicated AP3-like genes in Medicago truncatula Plant Journal 73: 663-675

Sainz M, Pérez-Rontomé C, Ramos J, Mulet JM, James EK, Bhattacharjee U, Petrich JW, Becana M (2013) Plant hemoglobins may be maintained in functional form by reduced flavins in the nuclei, and confer differential tolerance to nitro-oxidative stress Plant Journal 76: 875-887

Ríos G, Cabedo M, Rull B, Yenush L, Serrano R, Mulet JM (2013) Role of the yeast multidrug transporter Qdr2 in cation homeostasis and the oxidative stress response FEMS Yeast Research 13: 97-106

Bissoli G, Niñoles R, Fresquet S, Palombieri S, Bueso E, Rubio L, García-Sánchez MJ, Fernández JA, Mulet JM, Serrano R (2012) Peptidyl-prolyl cis-trans isomerase ROF2 modulates intracellular pH homeostasis in Arabidopsis Plant Journal 70: 704-716

Kahm M, Navarrete C, Llopis-Torregrosa V, Herrera R, Barreto L, Yenush L, Ariño J, Ramos J, Kschischo M (2012) Potassium starvation in yeast: mechanisms of homeostasis revealed by mathematical modeling PLoS Computational Biology 8: e1002548

Barreto L, Canadell D, Petrezselyova S, Navarrete C, Maresova L, Perez-Valle J, Herrera R, Olier I, Giraldo J, Sychrova H, Yenush L, Ramos J, Arino J (2011) A genomewide screen for tolerance to cationic drugs reveals genes important for potassium homeostasis in Saccharomyces cerevisiae Eukaryotic Cell 10: 1241-1250

Merchan S, Pedelini L, Hueso G, Calzada A, Serrano R, Yenush L (2011) Genetic alterations leading to increases in internal potassium concentrations are detrimental for DNA integrity in Saccharomyces cerevisiae Genes to Cells 16: 152-65

Mulet JM (2011) Letter to the editor regarding the article by Paganelli et al. Chemical Research in Toxicology 24: 609

Casado C, Yenush L, Melero C, Ruiz Mdel C, Serrano R, Pérez-Valle J, Ariño J, Ramos J (2010) Regulation of Trk-dependent potassium transport by the calcineurin pathway involves the Hal5 kinase FEBS Letters 584: 2415-2420

Pérez-Valle J, Rothe J, Primo C, Martínez Pastor M, Ariño J, Pascual-Ahuir A, Mulet JM, Serrano R, Yenush L (2010) The Hal4 and Hal5 protein kinases are required for the general control of carbon and nitrogen uptake and metabolism Eukaryotic Cell 9: 1881-1890

Hoeberichts FA, Perez-Valle J, Montesinos C, Mulet JM, Planes MD, Hueso G, Yenush L, Sharma SC, Serrano R (2010) The role of K+ and H+ transport systems during glucose- and H2O2-induced cell death in Saccharomyces cerevisiae Yeast 27: 713-725

Muñoz-Bertomeu J, Cascales-Miñana B, Mulet JM, Baroja-Fernández E, Pozueta-Romero J, Kuhn JM, Segura J, Ros R (2009) Plastidial Glyceraldehyde-3-Phosphate Dehydrogenase Deficiency Leads to Altered Root Development and Affects the Sugar and Amino Acid Balance in Arabidopsis Plant Physiology 151: 541-558

Gimeno J, Gadea J, Forment J, Pérez-Valle J, Santiago J, Martínez-Godoy MA, Yenush L, Bellés JM, Brumós J, Colmenero-Flores JM, Talón M, Serrano R (2009) Shared and novel molecular responses of mandarin to drought Plant Molecular Biology 70: 403- 420

Alejandro S, Rodriguez PL, Bellés JM, Yenush L, Garcia-Sanchez MJ, Fernandez JA, Serrano R (2007) An Arabidopsis quiescin-sulfhydryl oxidase regulates cation homeostasis at the root symplast-xylem interface EMBO Journal 26: 3203-3215

Pérez-Valle J, Jenkins H, Merchan S, Montiel V, Ramos J, Sharma S, Serrano R, Yenush L (2007) Key role for intracellular K+ and protein kinases Sat4/Hal4 and Hal5 in the plasma membrane stabilization of yeast nutrient transporters Molecular and Cellular Biology 27: 5725-5736

Portillo F, Mulet JM, Serrano R (2005) A Role for the non-phosphorylated Form of Yeast Snf1: Tolerance to Toxic Cations and Activation of Potassium Transporter FEBS letters 579: 512-516

Yenush L, Merchan S, Holmes J, Serrano R (2005) pH-Responsive, posttranslational regulation of the Trk1 potassium transporter by the type 1-related Ppz1 phosphatase Molecular and Cellular Biology 25: 8683-8692

Mulet JM, Alemany B, Ros R, Calvete JJ, Serrano R (2004) Expression of a Plant Serine O-acetyltransferase in Saccharomyces cerevisiae Confers Osmotic Tolerance and Creates and Alternative Pathway for Cysteine Biosynthesis Yeast 21: 303-312

Merchan S, Bernal D, Serrano R, Yenush L (2004) Response of the yeast Mpk1 MAP kinase pathway to increases in internal turgor pressure caused by loss of the Ppz protein phosphatases Eukaryotic Cell 3: 100-107

Mulet JM, Alejandro S, Romero C, Serrano R (2004) The Trehalose Pathway and Intracellular Glucose Phosphates as Modulators of Potassium Transport and General Cation Homeostasis in Yeast Yeast 21: 569-582

Ruiz A, Yenush L, Ariño J (2003) Regulation of ENA1 Na(+)-ATPase Gene Expression by the Ppz1 Protein Phosphatase Is Mediated by the Calcineurin Pathway Eukaryotic Cell 2: 937-948

Rausell A, Kanhonou R, Yenush L, Serrano R, Ros R (2003) The translation initiation factor eIF1A is an important determinant in the tolerance to NaCl stress in yeast and plants Plant Journal 34: 1-11

Patel S, Yenush L, Rodriguez PL, Serrano R, Blundell TL (2002) Crystal Structure of an Enzyme Displaying both Inositol-polyphosphate-1-Phosphatase and 3´-Phosphoadenosine-5´-phosphate Phosphatase Activities: A Novel Target of Lithium Therapy Journal of Molecular Biology 315: 677-685

Mulet JM, Serrano R (2002) Simultaneous Determination of Potassium and Rubidium Content in Yeast Yeast 19: 1295-1298

Yenush L, Mulet JM, Ariño J, Serrano R (2002) The Ppz Protein Phosphatases are Key Regulators of K+ and pH Homeostasis: Implications for Salt Tolerance, Cell Wall Integrity and Cell Cycle Progression EMBO Journal 21: 920-929

Forment J, Mulet JM, Vicente O, Serrano R (2002) The Yeast SR Protein Kinase Sky1p Modulates Salt Tolerance, Membrane Potential and the Trk1,2 Potassium Transporter Biochimica et Biophysica Acta 1565: 36-40

Yenush L, Belles JM, Lopez-Coronado JM, Gil-Mascarell R, Serrano R, Rodriguez PL (2000) A novel target of lithium therapy FEBS Letters 467: 321-325

Albert A, Martinez-Ripoll M, Espinosa-Ruiz A, Yenush L, Culiañez-Macia FA, Serrano R (2000) The X-ray structure of AtHal3 provides the structural basis for the activity of a regulatory subunit involved in signal transduction Structure 8: 961-969

Mulet JM, Leube MP, Kron SJ, Ríos G, Fink GR, Serrano R (1999) A Novel Mechanism of Ion Homeostasis and Salt Tolerance in Yeast: the Hal4 and Hal5 Protein Kinases Modulate the Trk1- Trk2 Potassium Transporter Molecular and Cellular Biology 19: 3328-3337

Líneas de investigación actuales

EVALUACIÓN EN SISTEMAS MODELO DEL POTENCIAL BIOESTIMULANTE DE DOS ALGAS FRENTE A CONDICIONES DE ESTRÉS ABIÓTICO. 14/11/25 – 13/04/26

Entidad financiadora: Q’OMER BIOACTIVE INGREDIENTS S.L.

IP: Rosa Porcel

IDENTIFICACION Y CARACTERIZACION DE NUEVOS MECANISMOS REGULADORES QUE GOBIERNAN LOS FLUJOS DE POTASIO EN ARABIDOPSIS (PID2022-137193NB-I00) 01/09/2023 – 31/08/2026

Entidad financiadora: Agencial Estatal de Investigación (Co-financiado con Fondos FEDER)

IP: Lynne Yenush y José Miguel Mulet

MODELO DE EVALUACIÓN DE EFECTOS BIOESTIMULANTES EN CULTIVOS CON CONDICIONES DE ESTRÉS ABIÓTICO: ESCASEZ DE AGUA Y BAJA FERTILIZACIÓN (MODELCALBIOSTRESS) (CPP2022-009965) 02/10/23 – 01/10/26

Entidad financiadora: Agencia Estatal de Investigación. I + D Colaborativa competitiva.

IP: José Miguel Mulet

UTILIZACIÓN DE PLANTAS HALÓFITAS PARA PROGRAMAS DE MEJORA DEL BRÓCOLI. INDUCCIÓN DE TOLERANCIA A LA SALINIDAD. SALINOBROC (CPP2022-009860) 01/09/23 – 31/08/26.

Entidad financiadora: Agencia Estatal de Investigación. I + D Colaborativa competitiva.

IP: José Miguel Mulet

Líneas Anteriores

EVALUACIÓN EN SISTEMAS MODELO DEL POTENCIAL BIOESTIMULANTE FRENTE AL ESTRÉS ABIÓTICO DE 8 PRODUCTOS DE ORIGEN NATURAL. 03/02/25 – 03/08/25

Entidad financiadora: SINYENT ENSAYOS Y DESARROLLOS AGRARIOS SL.

IP: Rosa Porcel

NUTRICIO DE POTASSI I ESTRES ABIOTIC EN BRASSICA (AICO/2021/352) 01/01/2021 – 01/01/2024

Entidad financiadora: Generalitat Valenciana

IP: Lynne Yenush

EVALUACIÓN DEL EFECTO BENEFICIOSO DE LA COMBINACIÓN DE DIFERENTES BIOESTIMULANTES COMERCIALES (EXTRACTOS DE PRODUCTOS NATURALES Y MICROBIANOS) BAJO CONDICIONES DE ESTRÉS SALINO EN PLANTAS DE INTERES AGRONÓMICO (PAID-06-22) 01/01/2023 – 31/12/2024

Entidad financiadora: Universitat Politècnica de València

IP: Rosa Porcel

DESARROLLO DE FORMULADOS BIOESTIMULANTES Y BIOFERTILIZANTES INNOVADORES DE ORIGENNATURAL (CALBIO) DESTINADOS A LA AGRICULTURA CONVENCIONAL Y ECOLÓGICA. ESTUDIO CIENTÍFICO DE EFECTOS SINÉRGICOS ENTRE BIOACTIVOS MICROBIANOS Y NO MICROBIANOS 08/06/2021 – 08/06/2023

Entidad financiadora: CALDIC IBERICA, S.L.

IP: JM Mulet

ESTUDIO DE REGULADORES DE CANALES DE POTASIO EN EL CONTROL DE LA APERTURA ESTOMATICA Y DE RESISTENCIA A SEQUIA (PID2019-104054GB-I00) 01/06/2020 – 01/06/2023

Entidad financiadora: Ministerio de Ciencia e Innovación y Universidades

IP: Lynne Yenush y JM Mulet

APROXIMACIONES MOLECULARES PARA INCREMENTAR LA TOLERANCIA A SALINIDAD Y SEQUIA DEL BROCOLI (RTC-2017-6468-2) 9/2018-06/2022

Entidad financiadora: Ministerio de Ciencia e Innovación y Universidades

IP: JM Mulet

Caracterización Molecular y Fisiológica de Dianas para la Optimización del Uso de Agua en Plantas (AICO/2018/300) 01/01/2018 – 01/01/2020

Entidad financiadora: Generalitat Valenciana

IP: Lynne Yenush

DESCIFRANDO LA REGULACION DE TRANSPORTADORES DE POTASIO EN PLANTAS Y LEVADURAS (BIO2016-77776-P) 1/2017-12/2019

Entidad financiadora: MINISTERIO DE ECONOMÍA Y COMPETITIVIDAD/FEDER

IP: Lynne Yenush y JM Mulet

PAPEL DEL TRAFICO DE PROTEINAS EN LA HOMEOSTASIS DE IONES Y NUTRIENTES EN LEVADURA Y PLANTAS (BFU2011-30197-C03-03) 01/2012-11/2015

Entidad financiadora: MINISTERIO DE ECONOMIA Y EMPRESA/FEDER

IP: Lynne Yenush y JM Mulet

Caracterización molecular del gen CRIO4 de remolacha y su aplicación en el desarrollo de líneas tolerantes a estrés por frío. (Primeros proyectos de investigación-1496), 01-11-2010/31-10-2012.

Entidad financiadora: Universitat Politècnica de València

IP: José Miguel Mulet

Rutas de Transduccion de Señales en la Regulacion de la Homeostasis Ionica. BFU2008-04188-C03-02.

Entidad financiadora: Ministerio de Economía y Competitividad/FEDER

IP: Lynne Yenush

Publicaciones y libros de divulgación

Porcel, Rosa (2024). Plantas que nos ayudan. Destino. 978-84-233-6643-9

Mulet, José Miguel (2023). Comemos lo que somos. Ediciones Destino. 978-8423362776

Mulet, José Miguel (2021). Ecologismo real. Ediciones Destino. 978-84-233-5920-2

Porcel, Rosa (2020). Eso no estaba en mi libro de Botánica. Editorial Guadalmazán. 978-8417547271

Mulet, José Miguel (2019). ¿Qué es la vida saludable? Destino. 978-8423356034

Mulet, José Miguel (2018). ¿Qué es comer sano? Destino. 978-8423354030

Mulet, José Miguel (2017). Transgénicos sin miedo. Destino. 978-8423352425