Staff Researchers
Hired Personnel and Interns
Fita-Torró J, Swamy KBS, Pascual-Ahuir, A, Proft, M. Divergence of alternative sugar preferences through modulation of the expression and activity of the Gal3 sensor in yeast. Molecular Ecology (2023).
doi:10.1111/mec.16954
Garrido-Huarte José Luis, Fita-Torró Josep, Viana Rosa, Pascual-Ahuir Amparo, Proft Markus. (2023). Severe acute respiratory syndrome coronavirus-2 accessory proteins ORF3a and ORF7a modulate autophagic flux and Ca2+ homeostasis in yeast. Frontiers in Microbiology, 14. https://doi.org/10.3389/fmicb.2023.1152249
Pascual-Ahuir Giner, María Desamparados; Proft, Markus Hans. (2020)
The mission of AIMS Bioengineering, an open-access forum to bring together Biological and Engineering Sciences. AIMS Bioengineering, 1 (7), 60 – 61.
10.3934/bioeng.2020006Pascual-Ahuir Giner, María Desamparados; Fita-Torró, Josep; Proft, Markus Hans. (2020)
Capturing and Understanding the Dynamics and Heterogeneity of Gene Expression in the Living Cell . International Journal of Molecular Sciences, 21 (21), 1 – 19.
10.3390/ijms21218278Pascual-Ahuir Giner, María Desamparados; González-Cantó, Eva; Juyoux, Pauline; Pable, Julia; Poveda-Huertes, Daniel; Saiz-Balbastre Sandra … Proft, Markus Hans. (2019)
Dose dependent gene expression is dynamically modulated by the history, physiology and age of yeast cells. Biochimica et Biophysica Acta (BBA) – Gene Regulatory Mechanisms, 4 (1862), 457 – 471.
10.1016/j.bbagrm.2019.02.009Vanacloig-Pedrós, Mª Elena; Lozano-Pérez, Carlos; Alarcon, B.; Pascual-Ahuir Giner, María Desamparados; Proft, Markus Hans. (2019)
Live-cell assays reveal selectivity and sensitivity of the multidrug response in budding yeast. Journal of Biological Chemistry, 35 (294), 12933 – 12946.
10.1074/jbc.RA119.009291
Vanacloig-Pedros E, Bets-Plasencia C, Pascual-Ahuir A, Proft M (2015) Coordinated Gene Regulation in the Initial Phase of Salt Stress Adaptation Journal of Biological Chemistry 290: 10163-10175
Timón Gómez, Alba; Sanfeliu-Redondo, D.; Pascual-Ahuir Giner, María Desamparados; Proft, Markus Hans. (2018)
Regulation of the Stress-Activated Degradation of Mitochondrial Respiratory Complexes in Yeast. Frontiers in Microbiology (9) – .
10.3389/fmicb.2018.00106Manzanares-Estreder, Sara; Pascual-Ahuir Giner, María Desamparados; Proft, Markus . (2017)
Stress-Activated Degradation of Sphingolipids Regulates Mitochondrial Function and Cell Death in Yeast. Oxidative Medicine and Cellular Longevity, 278345, 1 – 15.
10.1155/2017/2708345Pascual-Ahuir Giner, María Desamparados; Manzanares-Estreder, Sara; Proft, Markus. (2017)
Pro- and Antioxidant Functions of the Peroxisome-Mitochondria Connection and Its Impact on Aging and Disease.. Oxidative Medicine and Cellular Longevity, 986841, – .
10.1155/2017/9860841Manzanares-Estreder, Sara; Joan Espí Bardisa; B Alarcon; Pascual-Ahuir Giner, María Desamparados; Proft ., Markus Hans. (2017)
Multilayered control of peroxisomal activity upon salt stress in Saccharomyces cerevisiae. Molecular Microbiology, 5 (14), 851 – 868.
10.1111/mmi.13669Pascual-Ahuir Giner, María Desamparados; Manzanares-Estreder, Sara; Timón Gómez, Alba; Proft ., Markus Hans. (2017)
Ask yeast how to burn your fats: lessons learned from the metabolic adaptation to salt stress. Current Genetics, 1 (64), 63 – 69.
10.1007/s00294-017-0724-5Vanacloig-Pedrós, Elena; Proft, Markus Hans; Pascual-Ahuir Giner, María Desamparados. (2016)
Different Toxicity Mechanisms for Citrinin and Ochratoxin A Revealed by Transcriptomic Analysis in Yeast. Toxins, 1 (8), 1 – 20.
10.3390/toxins8100273
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Rienzo A,Poveda-Huertes Dl,Aydin S,Buchler NE, Pascual-Ahuir A, Proft M (2015)
Different Mechanisms Confer Gradual Control and Memory at Nutrient- and Stress-Regulated Genes in Yeast
Molecular and Cellular Biology 35: 3669-3683
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Pascual-Ahuir A, Vanacloig-Pedros E, Proft M (2014)
Toxicity mechanisms of the food contaminant citrinin: application of a quantitative yeast model
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Martínez-Montañés F, Rienzo A, Poveda-Huertes D, Pascual-Ahuir A, Proft M (2013)
Activator and Repressor Functions of the Mot3 Transcription Factor in the Osmostress Response of Saccharomyces cerevisiae
Eukaryotic Cell 12: 636-647
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Dolz-Edo L, Rienzo A, Poveda-Huertes D, Pascual-Ahuir A, Proft M (2013)
Deciphering Dynamic Dose Responses of Natural Promoters and Single cis Elements upon Osmotic and Oxidative Stress in Yeast
Molecular and Cellular Biology 33: 2228-2240
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Timón-Gómez A, Proft M, Pascual-Ahuir A (2013)
Differential regulation of mitochondrial pyruvate carrier genes modulates respiratory capacity and stress tolerance in yeast
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Pascual-Ahuir A, Proft M (2012)
Quantification of Protein-DNA Interactions by In Vivo Chromatin Immunoprecipitation in Yeast
Methods in Molecular Biology 809: 149-56
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Rienzo A, Pascual-Ahuir A, Proft M (2012)
The use of a real-time luciferase assay to quantify gene expression dynamics in the living yeast cell
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Montañés FM, Pascual-Ahuir A, Proft M (2011)
Repression of ergosterol biosynthesis is essential for stress resistance and is mediated by the Hog1 MAP kinase and the Mot3 and Rox1 transcription factors
Molecular Microbiology 79: 1008-23
- Vendrell A, Martínez-Pastor M, González-Novo A, Pascual-Ahuir A, Sinclair DA, Proft M, Posas F (2011)
Sir2 histone deacetylase prevents programmed cell death caused by sustained activation of the Hog1 stress-activated protein kinase
EMBO Reports 12: 1062-1068
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Martínez-Pastor M, Proft M, Pascual-Ahuir A (2010)
Adaptive changes of the yeast mitochondrial proteome in response to salt stress
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Martínez-Montañés F, Pascual-Ahuir A, Proft M (2010)
Toward a genomic view of the gene expression program regulated by osmostress in yeast
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Martínez Pastor M, Proft M, Pascual-Ahuir A (2009)
Mitochondrial function is an inducible determinant of osmotic stress adaptation in yeast
Journal of Biological Chemistry 284: 30307-30317
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Pascual-Ahuir A, Proft M (2007)
Control of stress-regulated gene expression and longevity by the Sch9 protein kinase
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Pascual-Ahuir A, Proft M (2007)
The Sch9 kinase is a chromatin-associated transcriptional activator of osmostress-responsive genes
EMBO Journal 26: 3098-108
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Pascual-Ahuir A, Struhl K, Proft M (2006)
Genome-wide location analysis of the stress-activated MAP kinase Hog1 in yeast
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Ali R,Pascual-Ahuir A, Marquez JA, Malik KA, Serrano R (2001)
Identification of Candida tropicalis HSR1, a gene of the heat-shock factor-related family, which confers salt tolerance in Saccharomyces cerevisiae
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Pascual-Ahuir A, Posas F, Serrano R, Proft M (2001)
Multiple levels of control regulate the yeast cAMP-response element-binding protein repressor Sko1p in response to stress
Journal of Biological Chemistry 276: 37373-37378
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Mendizabal I, Pascual-Ahuir A, Serrano R, de Larrinoa IF (2001)
Promoter sequences regulated by the calcineurin-activated transcription factor Crz1 in the yeast ENA1 gene
Molecular Genetics and Genomics 265: 801-11
- Proft M, Pascual-Ahuir A, de Nadal E, Ariño J, Serrano R, Posas F (2001)
Regulation of the Sko1 transcriptional repressor by the Hog1 MAP kinase in response to osmotic stress
EMBO Journal 20: 1123-1133
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Rep M, Proft M, Remize F, Tamás M, Serrano R, Thevelein JM, Hohmann S (2001)
The S. cerevisiae Sko1p transcription factor mediates HOG pathway-dependent osmotic regulation of a set of genes encoding enzymes implicated in protection from oxidative damage
Molecular Microbiology 40: 1067-1083
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Pascual-Ahuir A, Serrano R, Proft M (2001)
The Sko1p repressor and Gcn4p activator antagonistically modulate stress-regulated transcription in Saccharomyces cerevisiae
Molecular and Cellular Biology 21: 16-25
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Proft M, Serrano R (1999)
Repressors and Upstream Repressor Sequences of the Stress-Regulated ENA1 Gene in S. cerevisiae: bZIP Protein Sko1p Confers HOG-Dependent Osmotic Regulation
Molecular and Cellular Biology 19: 537-546
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Márquez A, Pascual-Ahuir A, Proft M, Serrano R (1998)
The Ssn6-Tup1 Repressor Complex of S. cerevisiae Is Involved in the Osmotic Induction of HOG-dependent and -independent Genes
EMBO Journal 17: 2543-2553
Pascual-Ahuir, A; Proft, M. (2012). Quatntification of Protein-DNA interactions by in vivo chromatin immunoprecipitation. Transcriptional Regulation: Methods and Protocols (149 – 156). Springer. 978-1-61779-375-2
Pascual-Ahuir Giner, María Desamparados (2022). Abstract . EN 6th AMR Conference. Basilea, Suiza.
Pascual-Ahuir Giner, María Desamparados; Proft, Markus Hans (2019). Live cell visualization of gene expression reveals its regulation by cell physiology, history, age and differential drug recognition. EN Meeting on Yeast Research: Origins, Insights, Breakthroughs . Cold Spring Harbor, USA.
Pascual-Ahuir Giner, María Desamparados; Proft ., Markus Hans (2017). Regulation of the Stress-Activated Degradation of Mitochondrial Respiratory Complexes in Yeast. EN Gordon Research Conference on Posttranslational Modification Networks. Hong Kong, China.
Pascual-Ahuir Giner, María Desamparados (2016). Stress response in eukaryote cells. EN Biotech Annual Congress (BAC 2016). X Congreso de la Federación Española de Biotecnólogos. (102 – 103). Gijón.
Pascual-Ahuir Giner, María Desamparados; Vanacloig-Pedrós, Mª ELENA; Proft ., Markus Hans (2015). Real time analysis of gene expression in living yeast cells as a novel approach for mycotoxin cell damage detection. EN 37th Mycotoxin Workshop. (140 – 140). Bratislava, Slovakia.
Pascual-Ahuir Giner, María Desamparados; Manzanares-Estreder, Sara; Proft ., Markus Hans (2015). Study of the function and regulation of peroxisomes in response to salt stress. EN XXXVIII Congreso de la Sociedad Española de Bioquímica y Biología Molecular (SEBBM 2015). (160 – 160). Valencia, España: Rubes Editorial, S.L. .
Pascual-Ahuir Giner, María Desamparados; Timón Gómez, Alba; Proft ., Markus Hans (2015). Mechanisms of mitochondrial quality control upon high respiration rates and stress in yeast. EN XXXVIII Congreso de la Sociedad Española de Bioquímica y Biología Molecular (SEBBM 2015). (150 – 150). Valencia, España: Rubes Editorial, S.L. .
Pascual-Ahuir Giner, María Desamparados; Vanacloig-Pedrós, Mª ELENA; Carolina; Proft ., Markus Hans (2015). Coordinated gene regulation in the initial phase of salt adaptation. EN XXXVIII Congreso de la Sociedad Española de Bioquímica y Biología Molecular (SEBBM 2015). (145 – 145). Valencia, España: Rubes Editorial, S.L. .
Timón Gómez, Alba; Proft ., Markus Hans; Pascual-Ahuir Giner, María Desamparados (2014). The function of mitochondrial pyruvate carriers in the adaptation of respiration capacity and stress tolerance in yeast. . EN MiP 2014 Symposium on Mitochondrial Physiology. (17 – 19). Obergurgl, Austria: Laner V, Gnaiger E, eds .
Pascual-Ahuir, A (2014). Real time analysis of gene expression in living yeast cells: Novel approach for accurate cell damage detection. EN 5th World Congress on Biotechnology. (141 – 141). Valencia, Spain: OMICS Group Journal.
Timón Gómez, Alba; Proft ., Markus Hans; Pascual-Ahuir Giner, María Desamparados (2014). Adaptation mechanisms of mitochondria to high respiration capacity and stress in yeast. EN Biotech Annual Congress (BAC 2014). VIII Congreso de la Federación Española de Biotecnólogos. (49 – 50). Barcelona, Spain: Federación Española de Biotecnólogos.
Timón-Gomez, A; Proft, M; Pascual-Ahuir, A (2013). Differential regulation of mitochondrial pyruvate carrier genes modulates respiratory capacity and stress tolerance in yeast. EN Cell Symposia. Mitochondria: from Signaling to Disease. (15 – 15). Lisboa.
Rienzo, A; Dolz-Edo, L; Pascual-Ahuir, A; Proft, M (2013). Real time analysis of gene expression in living yeast cells: Determination and molecular characterization of dynamic dose responses upon stress. EN 5th Congress of European Microbiologists (FEMS 2013). (45 – 45). Leipzig, Germany.
Rienzo, A; Pascual-Ahuir, A; Proft, M (2012). The use of a real time luciferase assay to quantify gene expression dynamics in the living yeast cell: a different way to check promoter activities under stress conditions. EN 2012 Microbial Stress Responses Gordon Research Conference. (28 – 28). South Hadley, USA.
Timón, A; Proft, M; Pascual-Ahuir, A (2012). Analysis of a mitochondrial protein family in yeast related to the human brain protein 44. EN Biotech Annual Congress (BAC 2012). VI Congreso de la Federación Española de Biotecnólogos. (104 – 104). Madrid.
Martinez-Pastor, M; Proft, M; Pascual-Ahuir, Amparo (2010). Mitochondrial function in the response to salt stress in yeast. EN 2010 GRC on Mitochondria & Chloroplasts. (75 – 75). Lucca, Italia: Abstracts.
Martínez-Montañés, F; Pascual-Ahuir, A; Proft, M (2010). Repression of ergosterol biosynthesis is essential for stress resistance and is mediated by the Hog1 MAP kinase and the Mot3 and Rox1 transcription factors. EN EMBO Conference on Gene Transcription in Yeast 2010. (93 – 93). San Feliu de Guixols, España: Abstracts.
Martinez-Pastor, M; Proft, M; Pascual-Ahuir, A (2010). The function of the mitochondria upon salt stress: Much more than the “power-house” of the yeast cell. EN Yeast Genetics and Molecular Biology Meeting 2010. (95 – 95). Vancouver, Canadá: Abstracts.
Fernando Martínez Montañés; Amparo Pascual-Ahuir; Markus Proft (2009). Regulation of Ergosterol Biosíntesis during the Adaptation to Osmotic Stress in the Yeast Saccharomyces cerevisiae. EN XXIV International Conference on Yeast Genetics and Molecular Biology. (160 – 160). Manchester, Reino Unido: Comite organizador.
Mar Martínez Pastor; Markus Proft; Amparo Pascual-Ahuir (2009). Mitochondrial function is an inducible determinant of osmotic stress adaptation in yeast. EN XXIV International Conference on Yeast Genetics and Molecular Biology. (112 – 112). Manchester, Reino Unido: Comite organizador.
Amparo Pascual-Ahuir (1999). Mecanismos de la inducción osmótica del gen HAL1. EN Euresco Conference on Gene Transcription in Yeast. Granada, España: EURESCO.
Amparo Pascual-Ahuir (1998). La represión transcripcional por Sko1p se encuentra bajo el control de la ruta HOG en Saccharomyces cerevisiae. EN STAR Congress on Cellular Response to Oxidative and Osmotic Stress 1999. Egmont aan Zee- Holanda: START.
